Back The Gold Coast
Chapters (90)
  1. Title Page
  2. Copyright Notice
  3. Contents
  4. Maps
  5. Chapter 1
  6. Chapter 2
  7. Chapter 3
  8. Chapter 4
  9. Chapter 5
  10. Chapter 6
  11. Chapter 7
  12. Chapter 8
  13. Chapter 9
  14. Chapter 10
  15. Chapter 11
  16. Chapter 12
  17. Chapter 13
  18. Chapter 14
  19. Chapter 15
  20. Chapter 16
  21. Chapter 17
  22. Chapter 18
  23. Chapter 19
  24. Chapter 20
  25. Chapter 21
  26. Chapter 22
  27. Chapter 23
  28. Chapter 24
  29. Chapter 25
  30. Chapter 26
  31. Chapter 27
  32. Chapter 28
  33. Chapter 29
  34. Chapter 30
  35. Chapter 31
  36. Chapter 32
  37. Chapter 33
  38. Chapter 34
  39. Chapter 35
  40. Chapter 36
  41. Chapter 37
  42. Chapter 38
  43. Chapter 39
  44. Chapter 40
  45. Chapter 41
  46. Chapter 42
  47. Chapter 43
  48. Chapter 44
  49. Chapter 45
  50. Chapter 46
  51. Chapter 47
  52. Chapter 48
  53. Chapter 49
  54. Chapter 50
  55. Chapter 51
  56. Chapter 52
  57. Chapter 53
  58. Chapter 54
  59. Chapter 55
  60. Chapter 56
  61. Chapter 57
  62. Chapter 58
  63. Chapter 59
  64. Chapter 60
  65. Chapter 61
  66. Chapter 62
  67. Chapter 63
  68. Chapter 64
  69. Chapter 65
  70. Chapter 66
  71. Chapter 67
  72. Chapter 68
  73. Chapter 69
  74. Chapter 70
  75. Chapter 71
  76. Chapter 72
  77. Chapter 73
  78. Chapter 74
  79. Chapter 75
  80. Chapter 76
  81. Chapter 77
  82. Chapter 78
  83. Chapter 79
  84. Chapter 80
  85. Chapter 81
  86. Chapter 82
  87. Chapter 83
  88. Acknowledgments
  89. By Kim Stanley Robinson from Tom Doherty Associates
  90. Copyright

Sandy begins his day on time. And while he’s only depending on himself, he stays on schedule. He tracks to a rundown area of the underlevel of Santa Ana, a mile or so north of South Coast Plaza, and unlocks the door to the warehouse he rents, after turning off all the alarms. Inside is his laboratory.

Today he starts with cytotoxicity assays, one of the most crucial parts of his work. Anyone can make drugs, after all; the trick is finding out if they’ll kill you or not without testing them personally. Or giving them to rats. Sandy doesn’t like killing rats. So he likes these assays.

Since the cornea’s epithelium will be the first place the drugs hit, epithelial cells get the first tests. A couple of days ago Sandy joined the crowd of biochem techs at the slaughterhouse and bought a package of cow eyeballs; now he takes them from the fridge and uses a device called a rubber policeman to scrape the epithelial cells off the basement membrane. Tapped into a petri dish with some growth medium, and a carefully measured dose of the drug in question—a new one, a variant of 3,4,5 trimethoxyamphetamine that he’s calling the Visionary—these cells will either proliferate or die or struggle somewhere in between, and staining them at the end of a week will tell the tale.

That assay set up, Sandy moves on to trickier stuff. The new drug’s effect on lymphocytes has to be checked as well, because blood will be carrying it a lot of the time. So Sandy begins a chromium release assay, injecting chromium 51 into lymphocytes, then centrifuging them so only the cells remain. At that point all the chromium in the mix is within the cells. Then the Visionary is added—in doses ranging from femptomolars up through picomolars, nanomolars, micromolars—and it all goes into a growth medium that should keep lymphocytes happy. But with the drug in there who knows. In any case dying or dead cells will release the chromium, and after another centrifuging, the free chromium found will be a good measure of the drug’s toxicity.

Later more tests of stationary cells and organ cells, particularly bone marrow cells, will be necessary. And eventually, after a lot of hours in the lab, Sandy will have a good idea of the Visionary’s toxicity. Neat. As for long-term negative effects of the new drug, well, that’s not so clear. That’s not in the guarantee. That’s not something he likes to think about, and neither does anybody else. None of these new drugs are well understood on the long-term level. But if there are problems down the road, they will no doubt come up with something, like they did for the various viral killers. Make the body into a micro-battlefield and win it all: the brain can finally prove it is smarter than viruses. Who knows what demon will fall next?