Back Resistance
Chapters (74)
  1. Title Page
  2. 1 - Portland, Oregon
  3. 2 - Vancouver, Canada
  4. 3 - Philadelphia, Pennsylvania
  5. 4 - Seattle, Washington
  6. 5 - Portland, Oregon
  7. 6 - Vancouver, Canada
  8. 7 - Portland, Oregon
  9. 8 - Vancouver, Canada
  10. 9 - Philadelphia, Pennsylvania
  11. 10 - Vancouver, Canada
  12. 11 - Vancouver, Canada
  13. 12 - Portland, Oregon
  14. 13 - Seattle, Washington
  15. 14 - Philadelphia, Pennsylvania
  16. 15 - Portland, Oregon
  17. 16 - Seattle, Washington
  18. 17 - Seattle, Washington
  19. 18 - Vancouver, Canada
  20. 19 - Seattle, Washington
  21. 20 - Philadelphia, Pennsylvania
  22. 21 - Portland, Oregon
  23. 22 - Philadelphia, Pennsylvania
  24. 23 - Vancouver, Canada
  25. 24 - Philadelphia, Pennsylvania
  26. 25 - Seattle, Washington
  27. 26 - Vancouver, Canada
  28. 27 - Portland, Oregon
  29. 28 - Honey Brook, Pennsylvania
  30. 29 - Seattle, Washington
  31. 30 - Vancouver, Canada
  32. 31 - Struble Lake, Pennsylvania
  33. 32 - Seattle, Washington
  34. 33 - Portland, Oregon
  35. 34 - Philadelphia, Pennsylvania
  36. 35 - Seattle, Washington
  37. 36 - Philadelphia, Pennsylvania
  38. 37 - Seattle, Washington
  39. 38 - Portland, Oregon
  40. 39 - Miami, Florida
  41. 40 - Seattle, Washington
  42. 41 - Seattle, Washington
  43. 42 - Philadelphia, Pennsylvania
  44. 43 - Seattle, Washington
  45. 44 - Mt. Airy, Philadelphia, Pennsylvania
  46. 45 - Seattle, Washington
  47. 46 - Philadelphia, Pennsylvania
  48. 47 - Seattle, Washington
  49. 48 - Mt. Airy, Philadelphia, Pennsylvania
  50. 49 - Mt. Airy, Philadelphia, Pennsylvania
  51. 50 - Seattle, Washington
  52. 51 - Mt. Airy, Philadelphia, Pennsylvania
  53. 52 - Philadelphia, Pennsylvania
  54. 53 - Philadelphia, Pennsylvania
  55. 54 - Philadelphia, Pennsylvania
  56. 55 - Philadelphia, Pennsylvania
  57. 56 - Brandywine Valley, Pennsylvania
  58. 57 - Philadelphia, Pennsylvania
  59. 58 - Philadelphia, Pennsylvania
  60. 59 - Philadelphia, Pennsylvania
  61. 60 - Philadelphia, Pennsylvania
  62. 61 - Philadelphia, Pennsylvania
  63. 62 - Philadelphia, Pennsylvania
  64. 63 - Philadelphia, Pennsylvania
  65. 64 - Philadelphia, Pennsylvania
  66. 65 - Philadelphia, Pennsylvania
  67. 66 - Philadelphia, Pennsylvania
  68. 67 - West Chester, Pennsylvania
  69. 68 - Glen Mills, Pennsylvania
  70. 69 - Philadelphia, Pennsylvania
  71. ACKNOWLEDGMENTS
  72. BY DANIEL KALLA FROM TOM DOHERTY ASSOCIATES
  73. ACCLAIM FOR DANIEL KALLA’S NOVELS
  74. Copyright Page

She pressed the remote, and the original slide with the circle of blue and purple streaks reappeared. “Today there are numerous other superbugs, but MRSA is the single most prevalent. Up until now, the only treatment available for MRSA involved expensive and potentially toxic intravenous medications, usually requiring hospital admission, thereby risking further spread.” She shook her head. “Aside from the immeasurable human cost, the annual expense of dealing with MRSA is estimated to be from six to eight billion dollars in the U.S. alone.”

Horton shifted from foot to foot, suddenly aware that all the eyes in the room were on her. “But SeptoMed might be able to forever alter that landscape,” she said, flushing as she spoke the painfully rehearsed lines Martineau had insisted on. She pressed the button. An organic chemical formula filled the screen, complete with chains and dashes linking Cs, Os, and Hs. “Ladies and gentlemen, allow me to introduce Oraloxin.

“Oraloxin represents a brand-new class of antibiotics which we’ve termed membrocidals.” She advanced to the next slide, which showed a spherical bacterium occupying most of the screen. “This is a single MRSA cell. Note the thickness of the cell wall, which is the bacterial equivalent of a coat of armor.” From the side of the screen an animated V-shaped structure swooped toward the cell and dug into the cell wall like an angry hornet. “This model simulates what happens when a molecule of Oraloxin binds to the bacterial cell wall.” As the “V” penetrated deeper, the cell began to fissure, like an egg cracking in slow motion. Then the two halves separated and the cell’s contents spewed out. The rest of the cell suddenly deflated like a balloon popping.

“In clinical testing, Oraloxin has shown remarkable effectiveness in combating MRSA,” Horton said, her tone somewhere between pride and self-consciousness. “With one-hundred-percent sensitivity. In other words, all MRSA infections have been susceptible to the medication thus far. And not just MRSA. Oraloxin performed equally well against other bacteria, even a multiresistant form of staph aureus that we genetically engineered in our lab.”

Horton flushed again as she heard the grumbling of approval from around the table. She cleared her throat, forcing to herself to pause before delivering the punch line. “Unlike most other MRSA treatments, no blood testing is required with Oraloxin.” She took a deep breath. “But I believe the most promising feature is the drug’s mode of delivery. It can be given as a once-daily, five-hundred-milligram pill for ten to fourteen days. In other words, Oraloxin represents the first outpatient and oral treatment available for MRSA.”

Horton clicked a button and the screen went white. She ran her prerehearsed closing line through her head before speaking it aloud. “Oraloxin is not only a powerful and brand-new weapon in the struggle against MRSA, but it will help keep the infection out of the hospital where it wreaks most of its havoc.” She exhaled slowly. “Thank you for your attention.”