Back We All Fall Down Save as PDF
Contents ( 132)
  1. Chapter
  2. One
  3. Chapter
  4. Two
  5. Chapter
  6. Three
  7. Chapter
  8. Four
  9. Chapter
  10. Five
  11. Chapter
  12. Six
  13. Chapter
  14. Seven
  15. Chapter
  16. Eight
  17. Chapter
  18. Nine
  19. Chapter
  20. Ten
  21. Chapter
  22. Eleven
  23. Chapter
  24. Twelve
  25. Chapter
  26. Thirteen
  27. Chapter
  28. Fourteen
  29. Chapter
  30. Fifteen
  31. Chapter
  32. Sixteen
  33. Chapter
  34. Seventeen
  35. Chapter
  36. Eighteen
  37. Chapter
  38. Nineteen
  39. Chapter
  40. Twenty
  41. Chapter
  42. Twenty-One
  43. Chapter
  44. Twenty-Two
  45. Chapter
  46. Twenty-Three
  47. Chapter
  48. Twenty-Four
  49. Chapter
  50. Twenty-Five
  51. Chapter
  52. Twenty-Six
  53. Chapter
  54. Twenty-Seven
  55. Chapter
  56. Twenty-Eight
  57. Chapter
  58. Twenty-Nine
  59. Chapter
  60. Thirty
  61. Chapter
  62. Thirty-One
  63. Chapter
  64. Thirty-Two
  65. Chapter
  66. Thirty-Three
  67. Chapter
  68. Thirty-Four
  69. Chapter
  70. Thirty-Five
  71. Chapter
  72. Thirty-Six
  73. Chapter
  74. Thirty-Seven
  75. Chapter
  76. Thirty-Eight
  77. Chapter
  78. Thirty-Nine
  79. Chapter
  80. Forty
  81. Chapter
  82. Forty-One
  83. Chapter
  84. Forty-Two
  85. Chapter
  86. Forty-Three
  87. Chapter
  88. Forty-Four
  89. Chapter
  90. Forty-Five
  91. Chapter
  92. Forty-Six
  93. Chapter
  94. Forty-Seven
  95. Chapter
  96. Forty-Eight
  97. Chapter
  98. Forty-Nine
  99. Chapter
  100. Fifty
  101. Chapter
  102. Fifty-One
  103. Chapter
  104. Fifty-Two
  105. Chapter
  106. Fifty-Three
  107. Chapter
  108. Fifty-Four
  109. Chapter
  110. Fifty-Five
  111. Chapter
  112. Fifty-Six
  113. Chapter
  114. Fifty-Seven
  115. Chapter
  116. Fifty-Eight
  117. Chapter
  118. Fifty-Nine
  119. Chapter
  120. Sixty
  121. Chapter
  122. Sixty-One
  123. Chapter
  124. Sixty-Two
  125. Chapter
  126. Sixty-Three
  127. Chapter
  128. Sixty-Four
  129. Chapter
  130. Sixty-Five
  131. Acknowledgments
  132. About the Author

“Couple of things,” he says, as he guides her toward another room in the ICU. “First of all, there have only been eight plague-related deaths today.”

“And that makes you smile?”

“There were eleven yesterday.”

Alana sees his point. In epidemiological terms, any decrease in the number of daily deaths or new victims in the acute phase of an outbreak represents a potential indicator of containment. But she’s not ready to concede. “The day’s not over.”

“Will be in fifteen minutes.” He nods to the digital clock above them that reads almost midnight.

“And you’re not even counting new cases in Naples,” she points out. “At least six more, with two deaths already.”

“We can only manage this outbreak city by city,” he says, undeterred. “If our model works here, then we can replicate it elsewhere.”

Alana isn’t buying it. “What are you not telling me, Byron?”

He steers her to another one of the rooms and motions to the patient who lies on the stretcher on the other side of the glass. With all the lines running into him, it takes Alana a moment to notice that he isn’t connected to a ventilator. Only a simple oxygen mask covers his face.

“This is Pietro Molaro,” Byron announces. “Pietro is the fifth patient to contract antibiotic-resistant plague. The other four are dead. Yesterday, it seemed certain Pietro was about to join them.”

Alana watches the patient reposition himself on the bed without help. “You mean he’s improving?”

Byron’s smile brightens.

“How?”

“Thanks to Claudio Dora.”

“Claudio? What does he have to do with this? He only left hospital today.”

“Yes, but the lab managed to extract the antibodies from the blood of a few survivors, including Claudio. Specifically, the immune globulins active against Yersinia. From that, they were able to genetically engineer enough antiserum to treat Pietro.”

“And it worked?” She waves the question away. “Well, obviously it did. But I thought it was going to take weeks or months to produce antiserum.”

“Originally, so did we. But the lab used an experimental technique. They cloned the DNA for the specific antibodies, then expressed them in a non-secreting myeloma cell line and purified the immune globulin from the supernatant.”

To most ears, the explanation would have sounded like gobbledygook, but Alana listens with growing excitement. She understands it means that scientists were able to splice the genetic information from Claudio’s antibodies into the genes of cancer cells and then use those rapidly multiplying malignant cells to produce enough of the protective antibodies to treat another patient.

“How much antiserum did they produce?” she asks.

Byron’s smile dims. “Enough for just one patient. But they’re ramping up to make more. With any luck, they’ll be able to produce hundreds of doses in the next couple of weeks.”

“Hundreds? That’s good. Very good. But it’s not a silver bullet. Not yet, at least. We’re going to need many more doses, and sooner than a couple weeks. By then the dam might’ve already burst.”